D&C Red 28, also known as Phloxine B, is a water-soluble xanthene dye that produces an intense, bluish-pink or red color with strong fluorescence. It is a highly effective colorant, providing a unique, vibrant shade that is very popular in the cosmetics industry. An interesting property is its ability to “stain” or develop its color based on the pH of the formulation, which is utilized in color-changing lipsticks.